杨枝云,李吉,潘隽,姜家富,刘裔道

目的：分析感染性结石尿培养病原菌分布特点及耐药性。方法：回顾性收集2018年1月至2022年8月在我院行 经皮肾镜碎石术（PCNL）治疗肾结石患者的结石成分分析及术前清洁中段尿培养。统计分析感染性结石尿培养病原菌 分布特点及耐药性。结果：本研究共纳入1394例行PCNL术治疗的肾结石患者，感染性结石447例（32.07%），其中174 例（38.93%）患者中段尿培养阳性，传统的产尿素酶细菌仅占25.99%。尿培养中以大肠埃希菌（50.85%），克雷伯菌属 （10.73%）、变形杆菌（8.47%）最为常见。药敏结果提示病原菌对常用的头孢菌素及喹诺酮类抗菌药物具有较高的耐药 率。结论：感染性结石尿培养病原菌以革兰阴性菌为主，大肠埃希菌最为常见，对常用的头孢菌素及喹诺酮类抗菌药物具 有较高的耐药性。

感染性结石；尿培养；脲酶；耐药性

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