何塞佩德罗,卡塔琳娜乔安娜

血液病患者经常出现脑血管并发症，包括缺血性中风、脑内和蛛网膜下腔出血、微出血、后部可逆性脑病综合征以及硬脑膜窦和脑静脉血栓形成（CVT）。在本次更新中，我们将回顾在骨髓增生性肿瘤、白血病、淋巴瘤、多发性骨髓瘤、POEMS、阵发性睡眠性血红蛋白尿（PNH）、血栓性血小板减少性紫癜（TTP）和镰状细胞病的背景下脑血管疾病管理的最新进展。伴有血液病的急性缺血性脑卒中，大血管闭塞时一般可取栓。静脉溶栓可用于骨髓增生性肿瘤和镰状细胞性贫血，但在其他疾病中，必须逐案评估出血风险。患有镰状细胞病和急性中风的患者需要经常输血。在PNH中，急性缺血性卒中患者必须进行抗凝治疗。大多数CVT患者可以使用低分子肝素（LMWH）进行急性治疗，即使是白血病患者也是如此。预防脑血栓事件的复发取决于对基础疾病的控制，在某些情况下与抗血栓药物相结合。最近在PHN和TTP治疗中引入特异性单克隆抗体显着降低了动脉和静脉血栓形成的风险。

中风；脑出血；脑静脉血栓形成；骨髓增生性肿瘤

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