作者
Gedeyon Getahun,Belay Erchafo,Lakew Abebe Gebretsadik,Mulugeta Chaka
文章摘要
早期诊断和立即开始治疗对于有效的结核病控制计划至关重要。治疗延误对个人和社区的疾病预后都有重要影响。2017年,在埃塞俄比亚南部哈迪亚区公共卫生设施接受治疗的前两个月的肺结核患者中评估了患者延误和相关因素。2017年3月10日至4月20日,对340名肺结核患者进行了定性研究三角化的基于设施的横断面研究。采用简单随机抽样技术选择研究卫生设施。在数据收集开始时,直接观察治疗短期用户被连续招募到研究中,直到达到预期的340个样本量。使用预先测试的结构化面试官问卷从参与者收集数据。多变量二元Logistic回归用于确定结核病治疗延迟的独立预测因子,这些变量是双变量分析中的候选变量。95%置信区间的P值<0.05被视为依赖变量和预测变量之间的统计学意义。来自七个诊断和治疗中心的340名肺结核患者入选,有效率为97.7%。在340名肺结核患者中,49.1%的患者出现延误。患者延迟的中位数为31。不能读写(AOR 6,95%可信区间(3.11-21.36),对肺结核缺乏了解(AOR 3.96,95%置信区间(2.286.86)),自我治疗(AOR:2,95%可信限(1.143.93),以及经济拮据(AOR2.092,95%置信限(1.113.945)是患者延迟的独立预测因素。近一半的患者在30天后寻求第一次咨询。无法阅读和写作、对肺结核的了解不足、自我治疗和经济限制被发现与患者延误有关。这可能导致结核病病例的持续存在,这可能导致出现多重耐药。为结核病控制计划实施精心设计的信息教育、沟通行为改变沟通策略,以克服患者延误的高流行率。
文章关键词
结核病治疗延误;肺结核;患者延迟;哈迪亚区;埃塞俄比亚
参考文献
[1] WHO, Global Tuberculosis Report 2013. World Health Organization.
[2] FMOH, (2012) Guidelines for clinical and programmatic management of TB, leprosy and TB/HIV in Ethiopia. FMOH, Addis Ababa.
[3] Tsegaye D, A. E., Mesele T, Tadesse T, etal, Delay in Seeking Health Care and associated Factors among Pulmonary Tuberculosis patients in North Wollo Zone, Northeast Ethiopia: /institutionBased crossectional Study. iMedPub Journals 2016 7(3) 1-7.
[4] WHO, Global Tuberculosis control.2010, WHO report.
[5] WHO, Global Tuberculosis Report 2014a, Geneva: World Health Organization(2014a). WHO report.
[6] WHO, World Health Organization (WHO) Global Tuberculosis Report, 2015, WHO report.
[7] Abebe G, Deribew A, and Apers L, Knowledge, health seeking behavior and perceived stigma towards tuberculosis among tuberculosis suspects in a rural community in southwest Ethiopia. PLOS ONE 5(10).
[8] FDREMOH, FDRE, Guideline for the national TB Leprosy Control Programme in Ethiopia Addis Ababa. Federal Ministry of Health Ethiopia, 2007.
[9] Dye C, W. B., (2012) The population dynamics and control of tuberculosis. PubMedGoogle Scholar 328(5980).
[10] Engeda EH, D. B., WoretaHK, KelkayMM, Ashenafie TD, eatal, (2016) Health Seeking Behaviour and Associated Factors among Pulmonary Tuberculosis Suspects in Lay Armachiho District, Northwest Ethiopia:Tuberc Res Treat.
[11] Yimer S, B. G., Alen G,, Diagnostic and treatment delay among pulmonary tuberculosis patients in Ethiopia: a cross sectional study. BMC Infectious Diseases2005, 5(112).
[12] Demissie M, L. B., Berhane Y, (2002) Patient and health service delay in the diagnosis of pulmonary tuberculosis in Ethiopia. BMC Public Health 22(23) 1-23.
[13] Belay M, B. G., Ameni G, Abebe F, etal, (2012)Diagnostic and treatment delay among Tuberculosis patients in Afar Region, Ethiopia: A cross-sectional study. BMC Public Health, 12(369) PP1-23.
[14] Gebeyehu E, A. M., Abeje G,, (2014) Factors Associated with Patient’s Delay in Tuberculosis Treatment in Bahir Dar City Administration, Northwest Ethiopia. BioMed Research International, Article ID: 701429.
[15] Mesfin MM, T. T., Tareke IG, Kifle YT, Karen WH, Richard MJ, etal, (2005)Delays and care seeking behavior among tuberculosis patients in Tigray of northern Ethiopia., Ethiopian Journal of Health Development 19(12) 7-12.
[16] Takarinda, H., AD, Nyathi B, Ngwenya M, Mutasa-ApolloT, SandyC, etal., Tuberculosis treatment delays and associated factors within the Zimbabwe national tuberculosis programme, 2016. MC Public Health 15(29) pp1-12.
[17] Cambanis A, Y. M., Ramsay A, Squire SB, ArbideI, Cuevas L, etal, (2016) Rural poverty and delayed presentation to tuberculosis services in Ethiopia, Tropical Medicine and International Health21(1365-3156).
[18] WHO, An in-depth analysis of the health-seeking behaviour of patients and health system responce in seven countries of eastern Meditrenian Region.2009WHO swizerland, Geneva. p. 1-48.
[19] Liam CK, T. B., Delay in the diagnosis and treatment of pulmonary tuberculosis in patient attending a University Teaching Hospital.1997, NT J TUBERC LUNG DIS 1(326-332).
[20] Salaniponi FM, H. A., Banda HJ,, Care seeking behaviour and diagnostic processes in patients with smear positive pulmonary tuberculosis in Malawi. INT J TUBERC LUNG DIS 1991 4(327-332).
[21] Kansiime C, K. S., Levi M, Asiimwe BB, KatambaA, etal, Health Service Delay among Pulmonary Tuberculosis Patients Presenting to a National Referral Hospital, Kampala, Uganda: A Cross Sectional Study. The Pan African Medical Journal, 2013, 15(84).
[22] Yimer S, G. Bjune, and Alene G, Diagnostic and treatment delay among pulmonary tuberculosis patients in Ethiopia: a cross sectional study.2005, BMC Infectious Diseases2005, 5(112) PP 1-8.
[23] Hamza A, D. M., Gare S, Teshome G,, (2015) Delay in Tuberculosis Diagnosis amongTuberculosis Patients at the Three Hospitals: Asella, Robe and Abomsa of Arsi Zone, Oromia Regional State, Open Access Library journal(2).
[24] Gele AA, B. G., AbebeF,, (2009) Pastoralism and delay in diagnosis of TB in Ethiopia. BMC Public Health 9(5).
[25] Yimer S, Bjune G, and Alene G, Diagnostic and treatment delay among pulmonary tuberculosis patients in Ethiopia: a cross sectional study.2005, BMC Infect Dis, 5(112).
Full Text:
DOI