谭丽华

血管性认知障碍，也就是VCI，其作为从轻度认知损害到痴呆的综合征，其是由各种显性、非显性脑血管病以及相关危险因素引发的。由于VD中晚期治疗效果不佳，对痴呆的研究转向了早期诊断及干预。而痴呆的诊断及干预仅在认知功能受损晚期才被识别，低估了血管原因所致认知损害的患病率，无法实现对存在认知损害但又未达到痴呆程度患者早期诊断及干预，易错过最佳治疗阶段。可通过早期干预脑血管病高危因素来改善认知损伤。相关研究表明高血脂通过引起血管损伤来增加脑卒中的危险，且饶颖[1]等人采用循证医学 Meta分析方法，对脑卒中认知障碍影响因素的研究结果进行系统评价，从数据研究的角度进一步明确了高血脂症是脑卒中认知障碍血管性影响因素之一。本文通过干预脑血管病高危因素之一的高血脂来改善脑卒中后认知功能障碍来说明研究价值及展望前景。

血管性认知障碍；脂代谢；研究价值

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