林 丽,张林飞,林倩文,张文娟,范家珊

二维（2D）过渡金属碳化物、碳氮化物和氮化物，简称MXenes，化学通式为Mn+1XnTx，因其表面具有丰富的官能团，良好的生物相溶性以及可降低药物毒副作用等优点，是新型功能材料在生物医药输送行为学上关注的焦点之一。这种独特的生物特性使MXenes成为一种有前途的替代性生物材料应用于多种生物医学领域，并揭示了许多新的基础科学发现。在此，本文系统地总结了碳化物MXenes相关生物材料的最新进展，特别关注合成方法、设计和表面工程策略、独特性质、生物效应，特别是性质-活性-生物界面上的效应关系。此外，经过精心设计的碳化物MXenes生物材料在生物传感器、抗菌药物、生物成像和治疗诊断学等领域都进行了详细说明。最后，我们在此基础上深入探讨了基于碳化物MXenes的生物材料未来发展面临的挑战和机遇，旨在促进其早日实现生物医学的临床应用。

二维结构；MXenes；复合材料；生物医学

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