梁紫楹,莫霄云,赵 航,杨舒妮

冠状动脉血管系统具有适应心肌需求的独特结构和功能，不能满足心肌需求会导致缺血、心绞痛和不良的心肌结果。非阻塞性心绞痛患者多存在冠状动脉微血管功能障碍(coronary microvascular dysfunction，CMD)，CMD与心房颤动和心室复极扭曲相关，增加死亡率、发病率和心脏骤停风险。CMD是心房颤动的独立危险因素，增加心室电不均匀性，并促进心脏疾病的进展。发病机制可能涉及氧化应激和供需矛盾导致的心肌缺血，通过扭曲心室复极化参数，增加室性心律失常和心脏骤停风险。

冠状动脉微血管功能障碍；室性心律失常；心房颤动

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