马 蓉,马晓梅

糖尿病肾病(DKD)在世界范围内的发病率正在迅速上升，主要是由于受2型糖尿病影响的个体人口不断增加。这一激增已转变为一个重大的全球问题，给已经在努力应对巨大需求的卫生保健系统带来了额外的压力。DKD的发病机制复杂，起源于高血糖，引发多种机制和途径:代谢、血流动力学、炎症和纤维化，最终导致肾脏损害。虽然目前的DKD治疗方案比以前的策略有所进步，但由于患者仍然存在疾病进展的残余风险，其有效性仍然受到一定限制。因此本文旨在对炎症与脂代谢紊乱对糖尿病肾病的影响进行综述，旨在为早期发现及预防糖尿病肾病提供有力的指导。

炎症；脂代谢紊乱；2型糖尿病；糖尿病肾病

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