马 榕

结直肠癌（CRC）是世界上三大常见癌症之一，也是相关癌症性死亡的第二大原因[1]。我国结直肠癌的发病率和死亡率也均呈上升趋势。氨酰基tRNA合成酶（ARSs）是所有细胞中蛋白质生物合成所必需的酶，它可以催化氨基酸与其同源转移RNA的连接反应[2]。目前有研究证明了ARSs通过非经典作用在结直肠癌的发生发展中起促进作用，且有相对应的靶向药物治疗。因此，研究并了解氨酰tRNA合成酶非经典作用在结直肠癌中的研究进展是必要的。

氨酰基tRNA合成酶；结直肠癌

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