张旺暾,郜 茜

胃食管反流病（GERD）是一种常见的消化系统疾病，主要表现为胃内容物反流至食管，导致反酸、烧心、咳嗽、咽痛等不适症状。胃食管反流症根据严重程度分为不同的类型。在本研究中讨论的类别是反流性食管炎（RE）、非糜烂性反流性疾病(NERD)和巴雷特食管。我们的研究通过对不同的研究结果的比较，发现相当多的胃食管反流患者有着焦虑和抑郁症状。胃食管反流病可通过扰乱日常活动对生活质量产生显著的负面影响。大多数胃食管反流患者都有使用抗酸药物来抑制胃酸的分泌。然而，即使在使用最强效的质子泵抑制剂（PPIs）的情况下，这些症状有时也难以控制，并且这些患者的反应率往往较低。根据临床数据分析，焦虑和抑郁与胃食管反流的不同症状表现有关。本研究的一个主要重点是探索焦虑和抑郁等心理影响及其与胃食管反流的相关性。这项研究还回顾了这些条件对年轻人群的影响。结论:胃食管反流患者的生活质量（QoL）因抑郁和焦虑而降低。

无症状糜烂性食管炎；心理因素；非糜烂性反流病；反流性食管炎；生活质量；抑郁症；焦虑症；胃食管反流病（GERD）；酸反流

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