复发性尿路感染的危险因子及预防

ISSN:2705-098X(P)

EISSN:2705-0505(O)

语言:中文

作者
张海谱
文章摘要
复发性尿路感染(rUTI)是临床泌尿系统最常见的疾病,研究表明它不同于尿路初次感染是一种不同的疾病。在健康女性,排尿功能失常及行为因素增加了rUTI的风险,性行为和绝经后女性雌激素缺乏与rUTI密切相关。如何预防rUTI主要包括三点:(1)危险行为改正和尽量避免风危险因子;(2)利用抗生素对微生物进行有针对性的预防措施;(3)非抗生素的预防措施,包括应用疫苗、补充雌激素及增加饮水量等。
文章关键词
复发性尿路感染;危险因子;预防
参考文献
[1] Epp A,Larochelle A,Lovatsis D,Walter JE,Easton W,Farrell SA,et al.Recurrent urinary tract infection.J Obstet Gynaecol Can.2010;32:1082–101. [2] Wagenlehner F,Wullt B,Ballarini S,et al.Social and economic burden of recurrent urinary tract infections and quality of life:a patient web-based study(GESPRIT).Expert Rev Pharmacoecon Outcomes Res 2018;18:107–17. [3] Scholes D,Hooton TM,Roberts PL,Stapleton AE,Gupta K,Stamm WE.Risk factors for recurrent urinary tract infection in young women. J Infect Dis.2000;182:1177–82. [4] Aydin A,Ahmed K,Zaman I,Khan MS,Dasgupta P.Recurrent urinary tract infections in women.Int Urogynecol J.2015;26:795–804. [5] Tsubouchi K,Arima H,Abe M,et al.Effect of pharmacotherapy for overactive bladder on the incidence of and factors related to urinary tract infection:a systematic review and meta-analysis.J Urol 2023;209:665–74. [6] Brain E,Geraghty RM,Cook P,et al.Risk of UTI in kidney stone formers:a matched-cohort study over a median follow-up of 19 years.World J Urol 2021;39:3095–101. [7] Grabe M,Bartetti R,Johansen TE,Cai T,Cek M,Koves B,et al.Guidelines on Urological Infections.EAU Guideline.2015. [8] Langford BJ,Brown KA,Diong C,et al.The benefits and harms of antibiotic prophylaxis for urinary tract infection in older adults.Clin Infect Dis 2021. [9] Hooton TM,Vecchio M,Iroz A,et al.Effect of increased daily water intake in premenopausal women with recurrent urinary tract infections:a randomized clinical trial.JAMA Intern Med 2018;178:1509–15. [10] Kochiashvili D,Khuskivadze A,Kochiashvili G,Koberidze G,Kvakhajelidze V.Role of the bacterial vaccine Solco-Urovac®in treatment and prevention of recurrent urinary tract infections of bacterial origin.Georgian Med News.2014;231:11–6. [11] Grin PM,Kowalewska PM,Alhazzan W,Fox-Robichaud AE.Lactobacillus for preventing recurrent urinary tract infections in women: Meta-analysis.Can J Urol.2013;20:6607–14. [12] Juthani-Mehta M,Van Ness PH,Bianco L,Rink A,Rubeck S,Ginter S,et al.Effect of cranberry capsules on bacteriuria plus pyuria among older women in nursing homes:A Randomized Clinical Trial. JAMA.2016;316:1879–87.
Full Text:
DOI