梁宝雯

周围神经损伤是临床上常见的创伤性疾病，其引发的功能障碍会严重影响患者的生活质量和心理健康。现有的治疗方法效果有限，难以实现完全的神经功能恢复，因此有必要开发新的疗法来改善周围神经损伤的恢复。近年来，通过干预细胞微环境以促进组织再生的干细胞疗法受到广泛关注。其中，外泌体作为细胞间通讯的重要载体，在旁分泌机制中发挥着关键作用，而脂肪源性干细胞作为外泌体的重要来源，展现出显著的治疗潜力，已被证明能够有效促进周围神经的再生。本综述介绍了脂肪干细胞源性外泌体在周围神经损伤修复中的机制、研究进展及其潜在应用，并讨论其面临的挑战和未来的研究方向。

脂肪源性干细胞；外泌体；周围神经损伤；神经再生

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