盛 赞,张 帆

胃食管反流病（GERD）是一种普遍的消化系统疾病，其发病率不断上升，严重影响患者的生活质量。本文综述了GERD治疗的最新进展，包括生活方式调整、心理干预、药物治疗、中医治疗、内镜下治疗及外科手术治疗。膳食和生活方式的调整，如减少辛辣、油腻食物的摄入、戒烟限酒、控制体重，对缓解症状至关重要。心理干预，包括药物和非药物治疗，能有效改善患者的心理状态和生活质量。药物治疗以抑酸剂为主，包括质子泵抑制剂（PPIs）、钾离子竞争性酸阻滞剂（P-CABs）和组胺H2受体拮抗剂（H2RAs），同时促动力药物和胃粘膜保护剂也发挥着重要作用。中医治疗通过病证结合、标本兼治，显示出积极效果。内镜下治疗技术，如射频治疗、贲门缩窄术等，提供了微创治疗的新选择。外科手术，包括腹腔镜抗反流术和减重手术，对药物治疗无效的患者提供了有效治疗手段。综合治疗策略，结合各种方法的优势，对控制病情更为有效。随着治疗手段的不断进步，为GERD患者提供了更多的治疗选择，以期达到更好的治疗效果和改善生活质量。

胃食管反流病；非药物治疗；药物治疗；内镜治疗；外科手术；治疗进展

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