郭薇薇,王 叶

蛋白质是生命的物质基础，蛋白质的周转循环对机体的各种生理活动是至关重要的。人体内蛋白质的合成、分解代谢是人体生命活动的基本保障之一。肌肉是人体中最普遍的部位之一，它由众多的肌细胞构建，并且根据其结构和功能的差异可以被划分为三种类别：平滑肌、心肌以及骨骼肌。在这些肌肉中，骨骼肌负责储存和代谢人体内的氨基酸和蛋白质，而它的正常运作和新陈代谢过程则会受到各种疾病因素的干扰。当蛋白质代谢紊乱时可能会影响能量供应和蛋白质合成，从而干扰肌肉生长和修复过程，导致骨骼肌减少，进而导致肌萎缩。在最近几年，全球“骨骼肌减少症”的患者数量持续上升，并且年龄也在逐步变小，这使得蛋白质代谢紊乱导致的骨骼肌肉减少变得越来越严重，这已经变成了公众健康面临的重大问题之一。本文就蛋白质代谢失衡对骨骼肌减少的影响进行系统总结并讨论。

蛋白质合成和分解；骨骼肌；肌少症

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