关节假体周围感染（PJI）是关节置换术后灾难性并发症，过去认为二期翻修是治疗PJI的“金标准”，最近更多的文献表明，一期翻修的感染控制率不低于二期翻修的感染控制率。随着人们对于翻修理念的提升，许多学者认为无论从经济、手术收益率及患者所承受的痛苦来说，二期手术治疗PJI所付出的代价都是巨大的。问题是，二期手术的缺点是否弥补了感染后更好的恢复，从术后并发症及术后关节评分角度来说似乎不尽人意。本文主要对比一期翻修与二期翻修术后的相关指标（术后感染控制率、术后并发症、死亡率及术后功能评分）、PJI术式选择的适应症两个方面进行阐述。

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