作者
何 杉
文章摘要
槲皮素是一种广泛存在于植物中的类黄酮,近年来因其潜在的抗炎、抗氧化和细胞信号通路调节特性而受到关注。牙根吸收是一种常见的口腔疾病,与各种细胞通路和因子的相互作用密切相关。本文综合了槲皮素影响与根吸收相关的细胞通路的机制,探讨了其对细胞增殖、凋亡、炎症反应和骨吸收等过程的影响。通过分析现有文献,我们旨在为牙根吸收的临床治疗和预防策略提供新的见解。
文章关键词
槲皮素;牙根吸收;抗炎;骨吸收
参考文献
[1] Patel,S.,et al.,Present status and future directions:Root resorption.Int Endod J,2022.55 Suppl 4(Suppl 4):p.892-921.
[2] Liu,Z.Y.and G.H.Yuan,[Clinical manifestations,pathogenesis,and management strategies for permanent teeth with external root resorption after trauma].Zhonghua Kou Qiang Yi Xue Za Zhi,2023.58(11):p.1191-1197.
[3] Wu,J.,et al.,The role of quercetin in NLRP3-associated inflammation.Inflammopharmacology,2024.32(6):p.3585-3610.
[4] Feng,Y.L.,L.P.Lu,and G.Y.Zhai,[Research progress on antitumor activity of quercetin derivatives].Zhongguo Zhong Yao Za Zhi, 2020.45(15):p.3565-3574.
[5] Sohrabi,M.,et al.,The release behavior and in vitro osteogenesis of quercetin-loaded bioactive glass/hyaluronic acid/sodium alginate nanocomposite paste.Int J Biol Macromol,2024.280(Pt 4):p.136094.
[6] Barrios-Nolasco,A.,et al.,Anti-Inflammatory Effect of Ethanolic Extract from Tabebuia rosea(Bertol.)DC.,Quercetin,and Anti-Obesity Drugs in Adipose Tissue in Wistar Rats with Diet-Induced Obesity.Molecules,2023.28(9).
[7] Guang,Q.,et al.,Quercetin alleviates inflammation induced by porcine reproductive and respiratory syndrome virus in MARC-145 cells through the regulation of arachidonic acid and glutamine metabolism.Vet Med Sci,2024.10(4):p.e1536.
[8] Wei,Y.,et al.,Quercetin Prevents Oxidative Stress-Induced Injury of Periodontal Ligament Cells and Alveolar Bone Loss in Periodontitis.Drug Des Devel Ther,2021.15:p.3509-3522.
[9] Yamaguchi,M.and S.Fukasawa,Is Inflammation a Friend or Foe for Orthodontic Treatment?:Inflammation in Orthodontically Induced Inflammatory Root Resorption and Accelerating Tooth Movement. Int J Mol Sci,2021.22(5).
[10] Cai,M.,et al.,Vascular Pericyte-Derived Exosomes Inhibit Bone Resorption via Traf3.Int J Nanomedicine,2023.18:p.7065-7077.
[11] Machado,N.,et al.,Influence of anti-allergic drugs used systemically on the process of root resorption during delayed tooth replantation:A study in rats.Dent Traumatol,2020.36(3):p.264-271.
[12] Spielman,R.,et al.,Challenges in differential diagnosis and treatment of cervical root resorption vs.root caries.Prim Dent J,2024. 13(2):p.65-70.
Full Text:
DOI