作者
张嘉璇,林蓉香,张家豪
文章摘要
心律失常是一种常见的心血管疾病,与高发病率和死亡率密切相关。以往的研究表明,利钠肽(包括脑钠肽、N端脑利钠肽前体、中区域前心房利钠肽)、肌钙蛋白和炎症等因素与心律失常的发生和发展密切相关。近年来,随着心律失常病理生理学研究的深入,发现纤维化和自身免疫标志物可能通过干扰成纤维细胞激活相关的电重构或心脏离子通道的功能,进而导致心律失常的发生和发展。检测这些标志物有助于提供早期诊断、疾病分型和预后预测的信息。本综述的目的在于系统地总结近年来关于心律失常新型生物标志物的研究进展,以期为临床诊疗提供更准确、更可靠的辅助信息。
文章关键词
心律失常;心房颤动;生物标志物
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