方尚云,姚 月,王炜业,曾翠敏

氟斑牙是因釉质发育期摄入过量氟元素所导致牙釉质发育异常的牙，其病理特征为釉质低矿化及耐酸性增强。研究表明，摄入的氟化物通过干扰成釉细胞的铁储存（降低Fth基因表达）和钙稳态（影响内质网Ca²⁺储存），导致氟斑牙釉质机械性能下降。在粘接修复中，氟斑牙釉质的超矿化表层显著影响粘接效果，因此需通过预处理优化。本文主要通过阐述氟斑牙釉质的结构特点、影响氟斑牙釉质严重程度的因素、氟斑牙釉质的粘接处理方法这三个方面为氟斑牙的粘接治疗提供理论依据。

氟斑牙；牙釉质粘结；釉质矿化异常；粘接系统

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