吴维财,李 曼,鲁 静,黄庆维,陈 红

尿毒症合并糖尿病是临床常见的危重病症，随着其患病率的逐年上升，血液透析作为治疗尿毒症的重要手段，广泛应用于临床。然而，长期透析导管的使用在改善患者生存质量的同时，也带来了诸多并发症，其中长期透析导管相关性感染（CRBSI）是最为常见的并发症之一。糖尿病患者由于免疫功能受损、血糖控制不良等因素，血液透析过程中发生CRBSI的风险较高。本文综合分析了尿毒症合并糖尿病患者血液透析中导管相关性感染的相关研究，探讨其发病机制、危险因素、预防与治疗策略，并结合现有文献，提出改进措施。研究发现，早期识别感染症状、优化透析导管使用管理、严格控制血糖、提高患者的免疫功能以及合理使用抗生素治疗是减少血液透析患者CRBSI发生率的关键。本文的研究为血液透析相关感染的防治提供了有益的参考。

尿毒症；糖尿病；血液透析；透析导管；导管相关性感染

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