沈阳阳,迪 吉

胃癌是全球常见的恶性肿瘤之一，严重威胁人类健康。据世界卫生组织国际癌症研究机构（IARC）发布的2020年全球癌症数据，胃癌新发病例约108.9万例，死亡病例约76.9万例，其发病率和死亡率在各类恶性肿瘤中均位居前列。本文系统梳理血脂异常与胃癌发生风险的流行病学研究进展。通过对国内外相关文献的综合分析，探讨总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇等血脂指标异常与胃癌发病风险之间的关联，并剖析可能的作用机制。现有研究表明，血脂异常与胃癌发生风险存在复杂关联，部分血脂指标异常可能增加胃癌患病风险，但也有研究结论存在分歧。深入探究两者关系，有助于揭示胃癌发病机制，为胃癌的早期预防、风险评估和干预提供新的理论依据和研究方向。

血脂异常；胃癌；流行病学；发病风险；关联分析

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