亚临床甲减（SCH）以血清促甲状腺激素（TSH）水平升高、游离甲状腺素（FT4）水平正常为特征，TSH处于4-10 mIU/L时是否干预尚无定论。本综述系统梳理该阈值区间的病理生理机制、临床风险、治疗效果及争议，结合最新循证医学证据，探讨个体化治疗策略，为明确亚临床甲减治疗阈值提供理论依据。

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