覃冰冰,陈海燕

脑血管意外是导致残疾和认知缺陷的主要原因。缺血性脑卒中病理机制涉及氧化应激、细胞凋亡与自噬、血脑屏障破坏及神经炎症等多重过程。MicroRNA（miRNA）作为关键调控分子，通过靶向相关基因参与这些病理环节，在缺血性脑卒中的发生、发展中发挥重要作用。本综述旨在总结近年来关于miRNA在缺血性脑卒中的研究进展，探讨其潜在的治疗价值。

MicroRNA；缺血性脑卒中；生物标志物；机制；治疗

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