林锦业,黄月艳

地中海贫血作为一种遗传性溶血性贫血疾病，在全球范围内，特别是在地中海沿岸、东南亚及中国南方等地区具有较高的发病率。随着医疗技术的进步，地中海贫血患者的生存期显著延长，然而与之相关的并发症，尤其是骨质疏松症，日益成为影响患者生活质量的重要问题。本综述梳理儿童地中海贫血患者骨质疏松症的流行病学特征、发病机制、影响因素、早期筛查与诊断及防治策略。

地中海贫血；骨质疏松症；铁过载；骨密度；儿童患者

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