支雄莉,Xiongli Zhi

目的：分析宫颈电热圈环形切除术联合干扰素栓和保妇康栓治疗子宫颈高级别上皮内病变的疗效以及对并发症发生率的影响。方法：选取72例于2020年01月－2022年04月期间到河北省张家口市第一医院接受诊治的子宫颈高级别上皮内病变患者作为研究样本，在随机数字表法的分组规则下将这72例患者进行分组，分别为常规组36例，给予组内患者宫颈电热圈环形切除术进行治疗，研究组36例，给予组内患者宫颈电热圈环形切除术联合干扰素栓和保妇康栓治疗。通过比较两组患者的临床疗效、并发症发生率、治疗满意度以及生活质量等指标来分析宫颈电热圈环形切除术联合干扰素栓和保妇康栓治疗的应用效果。结果：与常规组比较，研究组患者的临床疗效更加显著（P＜0.05）；研究组患者的并发症发生率较低（P＜0.05）；研究组患者的治疗满意度较高（P＜0.05）；研究组患者的生活质量明显优于常规组（P＜0.05）。结论：对于子宫颈高级别上皮病变患者来说，应采用宫颈电热圈环形切除术联合干扰素栓和保妇康栓治疗，这种治疗方式可以有效改善患者的生活质量，降低患者的并发症发生率，并提患者的治疗满意度以及临床疗效，应用效果显著。 Objective: To analyze the curative effect of cervical electrothermal loop resection combined with interferon suppository and Baofukang suppository in the treatment of high grade intraepithelial lesion of uterine neck and its influence on the incidence of complications.Methods:72 patients with cervical high-grade intraepithelial lesion who were treated in the First Hospital of Zhangjiakou City of Hebei Province from January 2020 to April 2022 were selected as the study samples. Under the rule of random number table, the 72 patients were divided into conventional group (36 cases) and the patients in the study group (36 cases).By comparing the clinical efficacy, complication rate, treatment satisfaction and quality of life of the two groups of patients, the effect of cervical electrothermal loop resection combined with interferon suppository and Baofukang suppository was analyzed.Results: Compared with the routine group, the clinical effect of the study group was more significant (P <0.05); the complication rate of the study group was lower (P <0.05); the satisfaction of the study group was higher (P <0.05); the quality of life of the study group was significantly better than the routine group (P <0.05).Conclusion: For the patients with high grade cervical epithelial lesions, the electrothermal loop resection combined with interferon suppository and Baofukang suppository should be used, which can effectively improve the quality of life of the patients, reduce the incidence of complications, and improve the patients’ satisfaction with treatment and clinical efficacy, with significant application effect.

宫颈电热圈环形切除术；干扰素栓；保妇康栓；子宫颈高级别上皮内病变 Cervical electrothermal loop resection; interferon suppository; baofukang suppository; cervical high-grade intraepithelial lesion

[1] 黄兴华,伞翠平,孙国丽,等.宫颈电热圈环形切除术联合干扰素栓和保妇康栓治疗子宫颈高级别上皮内病变的效果观察[J].临床医学工 程,2021,28(07):873-874. [2] 杨喆,李永杰,曹蕾,等.子宫颈高级别上皮内病变患者的治疗对策及转归[J]. 中国妇产科临床杂志,2021,22(04):356-359. [3] 余凌丽,王方,刘晓媛.子宫颈环形电切术与冷刀宫颈锥切术治疗高级别鳞状上皮内病变患者的临床疗效及预后[J].医疗装备,2021,34(11):117-119. [4] 何燕.积极心态感知联合健康教育对高级别子宫颈鳞状上皮内病变患者的影响[J].包头医学院学报,2021,37(03):96-100. [5] 封媛媛.高级别子宫颈鳞状上皮内病变经不同手术治疗的效果及术后复发危险因素[J].中外医学研究,2021,19(07):3-6. [6] 冯慧,马德勇,赵健.红色诺卡氏菌细胞壁骨架治疗子宫颈高级别鳞状上皮内病变的安全性和疗效研究[J].中国实用妇科与产科杂 志,2021,37(03):357-361. [7] 李静然,魏丽惠.子宫颈高级别上皮内病变治疗后 HPV 疫苗预防复发的研究进展[J].现代妇产科进展,2021,30(05):395-398. [8] 陈梽烈.锥切术后高级别子宫颈鳞状上皮内病变切缘阳性及二次手术病灶残留的相关因素研究[J].中国医学创新,2020,17(36):125-129. [9] 李卓艺,沈晓玲,谌丹.物理治疗子宫颈高级别鳞状上皮内病变的疗效和危险因素分析[J].中国妇幼保健,2020,35(23):4613-4615. [10] 李长忠,崔国英.重视高危型人乳头瘤病毒感染和子宫颈鳞状上皮内病变的过度诊治[J].中国实用妇科与产科杂志,2020,36(07):585-587. [11] 卢玉娟,杨志玲,王愚.宫腔镜下宫颈“图钉形”切除术治疗有生育要求的子宫颈高级别鳞状上皮内病变的临床探讨[J].中国医药导 报,2020,17(15):96-99.

点击下载PDF