李水英,谢达奇

目的：评价沙库巴曲缬沙坦钠片用于治疗高血压合并冠心病的疗效，及其预防和改善患者心肌重构的作用。方法：高血压合并冠心病患者60例，随机分为研究组和对照组。研究组给予沙库巴曲缬沙坦钠片；对照组给予缬沙坦胶囊。记录患者一般情况。分别于治疗前（T0）、治疗后1周（T1）、治疗后1个月（T2）、治疗后6个月（T3）、治疗后1年（T4），测量患者左上臂收缩压及舒张压；采用彩色多普勒超声诊断仪，测量患者左心室后壁厚度、左心室舒张末期内径、左室射血分数。

沙库巴曲缬沙坦；高血压；冠心病；心肌重构

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