王金强

目的 探讨腔镜甲状腺癌手术中应用纳米碳对甲状旁腺功能保护的应用效果。方法 选取2021年1月-2023年12月我院甲状腺外科收治需实施腔镜甲状腺癌手术切除治疗的患者144例，随机分两组，对照组实施常规手术切除治疗，研究组实施纳米碳辅助腔镜行手术切除治疗，对两组患者淋巴结清扫枚数、甲状腺损伤程度、血钙及血清PTH水平进行比较。结果 研究组清扫淋巴结数目更多（P＜0.05）；研究组甲状旁腺误切率更低，且术后淋巴结转移阳性率更高（P＜0.05）；研究组血钙及血清PTH水平更高（P＜0.05）。结论 在对甲状腺癌患者实施腔镜手术切除治疗时利用纳米碳进行辅助，可以提高术中对淋巴的清扫数量，同时不会对患者的甲状腺造成明显损伤，对术后血钙及血清PTH水平有显著的改善效果，因此临床推广价值较高。

腔镜甲状腺癌手术；纳米碳；甲状旁腺功能；淋巴结清扫

[1]张琪,王泽升,高金伟,等.腔镜甲状腺癌根治术联合甲状旁腺自体移植术对甲状旁腺功能恢复的影响[J].解放军医学杂 志,2023,48(4):437-444. [2] Li Q , Yu D , Peng J ,et al.Efficient Polytelluride Anchoring for Ultralong-Life Potassium Storage: Combined Physical Barrier and Chemisorption in Nanogrid-in-Nanofiber[J].Nano-Micro Letters, 2024(004):016. [3]覃湘泉,赵晶晶,罗佳,等.机器人辅助超精细被膜解剖技术在甲状腺癌手术中的应用:附 1045 例报告[J].中国普通外科杂 志,2023(11):1677-1686. [4] Slim K , Tilmans G ,Bob Valéry Occéan,et al.Meta-analysis of randomized clinical trials comparing robotic versus laparoscopic surgery for mid-low rectal cancers[J].Journal of Visceral Surgery, 2024, 161(2):76-89. [5]丁昱强,王猛,厉彦辰,等.双侧乳晕腋窝径路机器人在肥胖女性甲状腺癌手术中的应用[J].临床耳鼻咽喉头颈外科杂 志,2023,37(4):288-292. [6] Yitian H , Shupei Z , Yanjie C ,et al.Two-phase dual-signal-readout immunosensing platform based on multifunctional carbon nano-onions for ovarian cancer biomarker detection[J].Journal of Materials Chemistry, B. materials for biology and medicine, 2023(30):11. [7]顾建华,程宇,于娟,等.示踪用盐酸米托蒽醌注射液对甲状腺癌前哨淋巴结示踪疗效及对甲状旁腺功能的保护作用研究[J].中国临 床药理学杂志,2022,38(20):2392-2395. [8]李莉,王建军,曹俊宇,等.无充气腋窝入路与经胸乳入路腔镜甲状腺癌根治术的效果分析[J].实用医学杂志,2023,39(13):1669-1674. [9] Babar Z B , Rizwan K , Munir S .Multifunctional Smart Nano-membranes for the Removal of Oil-Based Pollutants from Marine Sources: A Tool for Sustainable Environment[J].Water, air and soil pollution, 2024(1):235. [10]赵万胜杨枋代瑞孙智强朱尧.甲状腺癌全切术中应用精细化甲状腺被膜解剖技术对喉返神经的影响[J].中国现代医学杂 志,2022,32(19):86-90. [11]余富杰,赵健洁,赵大威,等.机器人经口腔前庭入路与传统开放性甲状腺癌根治手术的对比研究[J].重庆医科大学学 报,2023,48(6):662-666. [12]王登欢,张冉,冯恩梓,等.经口腔前庭入路腔镜手术在甲状腺癌中央区淋巴结清扫中的有效性研究[J].临床耳鼻咽喉头颈外科杂 志,2022,36(7):6. [13] Varanese M , Arcieri S , Lauro A ,et al.Indocyanine Green Tattooing During Colonoscopy as a Guide to Laparoscopic Colorectal Cancer Surgery: A Literature Review[J].Surgical innovation, 2024(1):31. [14]徐嘉,王玉龙,康宁,等.自体荧光联合纳米碳在甲状腺术中识别甲状旁腺的临床应用[J].中华肿瘤防治杂志,2022,29(1):4. [15] Ghalkhani M , Mirzaie R A , Shahmoradi F ,et al.Achievement of an efficient oxygen reduction electrocatalyst based on carbon boosted with MnO x /MnCo 2 O 4 with excellent electrocatalytic activity in neutral media[J].Carbon Letters, 2024(1):34. [16]王哓艳,钟琦,房居高,等.甲状腺癌手术中双荧光显影识别中央区淋巴结及甲状旁腺的效果[J].中华医学杂 志,2024,104(12):938-943. [17] Ivan P R , Neil T F , Luis C V A ,et al.Methane and carbon dioxide adsorption on carbon nano-onions synthesized by the submerged arc-discharge method[J].Adsorption, 2024(1):30. [18]高金伟,王泽升,张琪,等.腔镜甲状腺癌根治术中甲状旁腺自体移植和原位保留的临床经验[J].实用医学杂 志,2022,38(22):2885-2887. [19] Selim M S , Azzam A M , Shenashen M A ,et al.Comparative study between three carbonaceous nanoblades and nanodarts for antimicrobial applications[J].Journal of Environmental Sciences, 2024(002):000. [20]林庆军,杜丽,林燕晖,等.分化型甲状腺癌甲状腺全切术中精细化甲状腺被膜解剖术与经环甲隙显露喉返神经法联合应用观察[J]. 山东医药,2023(30):25-28.

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